{
  "_id": "6acf5055d9de2f3f33fcac40",
  "Package": "hctrial",
  "Type": "Package",
  "Title": "Using Historical Controls for Designing Phase II Clinical Trials",
  "Version": "0.1.0",
  "Authors@R": "person(\"Dominic\", \"Edelmann\", email = \"dominic.edelmann@dkfz-heidelberg.de\",\nrole = c(\"aut\", \"cre\"))",
  "Description": "Provides functions for designing phase II clinical trials\nadjusting for the heterogeneity of the population using known\nsubgroups or historical controls.",
  "License": "GPL-2 | GPL-3",
  "RoxygenNote": "6.1.1",
  "Encoding": "UTF-8",
  "Repository": "https://edelmand21.r-universe.dev",
  "Date/Publication": "2018-12-20 15:38:13 UTC",
  "RemoteUrl": "https://github.com/edelmand21/hctrial",
  "RemoteRef": "HEAD",
  "RemoteSha": "a61383993f2ee07cc2a06bce92d097a985223839",
  "NeedsCompilation": "no",
  "Packaged": {
    "Date": "2026-10-14 09:01:37 UTC",
    "User": "root"
  },
  "Author": "Dominic Edelmann [aut, cre]",
  "Maintainer": "Dominic Edelmann <dominic.edelmann@dkfz-heidelberg.de>",
  "_user": "edelmand21",
  "_type": "src",
  "_file": "hctrial_0.1.0.tar.gz",
  "_fileid": "https://r2.ropensci.org/93078e4471960d7f0e00b85de1a07dfa39fffc010f26f6ad56f73d818d9843b2",
  "_filesize": 91365,
  "_sha256": "93078e4471960d7f0e00b85de1a07dfa39fffc010f26f6ad56f73d818d9843b2",
  "_expires": "2027-01-22T09:50:12.000Z",
  "_created": "2026-10-14T09:01:37.000Z",
  "_published": "2026-10-14T09:50:13.886Z",
  "_buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_jobs": [
    {
      "job": 115770093984,
      "time": 132,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11881582023"
    },
    {
      "job": 115770094113,
      "time": 87,
      "config": "linux-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11880899404"
    },
    {
      "job": 115770094041,
      "time": 137,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11884147303"
    },
    {
      "job": 115770094049,
      "time": 153,
      "config": "macos-release-arm64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11883458542"
    },
    {
      "job": 115769021376,
      "time": 156,
      "config": "source",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11880869289"
    },
    {
      "job": 115770094002,
      "time": 79,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "11881029556"
    },
    {
      "job": 115770094148,
      "time": 66,
      "config": "windows-devel-x86_64",
      "r": "4.7.0",
      "check": "OK",
      "artifact": "11880659582"
    },
    {
      "job": 115770094233,
      "time": 45,
      "config": "windows-oldrel-x86_64",
      "r": "4.5.3",
      "check": "OK",
      "artifact": "11881546776"
    },
    {
      "job": 115770094210,
      "time": 68,
      "config": "windows-release-x86_64",
      "r": "4.6.1",
      "check": "OK",
      "artifact": "11881218912"
    }
  ],
  "_upstream": "https://github.com/edelmand21/hctrial",
  "_commit": {
    "id": "a61383993f2ee07cc2a06bce92d097a985223839",
    "author": "edelmand21 <dominic.edelmann@gmail.com>",
    "committer": "GitHub <noreply@github.com>",
    "message": "Upload 1",
    "time": 1545320293
  },
  "_maintainer": {
    "name": "Dominic Edelmann",
    "email": "dominic.edelmann@dkfz-heidelberg.de",
    "login": "edelmand21",
    "description": "",
    "uuid": 19347872
  },
  "_distro": "resolute",
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 3.5.0",
      "role": "Depends"
    },
    {
      "package": "clinfun",
      "role": "Imports"
    },
    {
      "package": "GenBinomApps",
      "role": "Imports"
    },
    {
      "package": "stats",
      "role": "Imports"
    }
  ],
  "_owner": "edelmand21",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_stars": 0,
  "_contributors": [
    {
      "user": "edelmand21",
      "count": 1,
      "uuid": 19347872
    }
  ],
  "_userbio": {
    "uuid": 19347872,
    "type": "user",
    "name": "edelmand21",
    "followers": 1
  },
  "_downloads": {
    "count": 266,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/hctrial"
  },
  "_devurl": "https://github.com/edelmand21/hctrial",
  "_searchresults": 6,
  "_rbuild": "4.6.1",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/hctrial.html",
    "extra/manual.pdf",
    "extra/NEWS.html",
    "extra/NEWS.txt",
    "extra/readme.html",
    "extra/readme.md"
  ],
  "_homeurl": "https://github.com/edelmand21/hctrial",
  "_realowner": "edelmand21",
  "_cranurl": true,
  "_releases": [
    {
      "version": "0.1.0",
      "date": "2018-12-21"
    }
  ],
  "_exports": [
    "hist_end",
    "hist_interim",
    "hist_start",
    "strat_end",
    "strat_interim",
    "strat_start"
  ],
  "_help": [
    {
      "page": "hctrial",
      "title": "hctrial: A package for designing phase 2 clinical trials adjusting for heterogeneous populations.",
      "topics": [
        "hctrial-package",
        "hctrial"
      ]
    },
    {
      "page": "hist_end",
      "title": "Adjust a design based on historical controls at the end of the study using the covariate data of the patients accrued in stage 2.",
      "topics": [
        "hist_end"
      ]
    },
    {
      "page": "hist_interim",
      "title": "Adjust a design based on historical controls at interim using the covariate data of the patients accrued in stage 1.",
      "topics": [
        "hist_interim"
      ]
    },
    {
      "page": "hist_start",
      "title": "Initializes a design based on historical controls before the start of the study.",
      "topics": [
        "hist_start"
      ]
    },
    {
      "page": "strat_end",
      "title": "Adjust a subspace stratified design at the end of the study.",
      "topics": [
        "strat_end"
      ]
    },
    {
      "page": "strat_interim",
      "title": "Adjust a subspace stratified design at interim.",
      "topics": [
        "strat_interim"
      ]
    },
    {
      "page": "strat_start",
      "title": "Initializes a subspace stratified design before the start of the study.",
      "topics": [
        "strat_start"
      ]
    }
  ],
  "_readme": "https://github.com/edelmand21/hctrial/raw/HEAD/README.md",
  "_rundeps": [
    "clinfun",
    "GenBinomApps",
    "mvtnorm"
  ],
  "_score": 2.6989700043360187,
  "_indexed": true,
  "_nocasepkg": "hctrial",
  "_universes": [
    "edelmand21"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "0.1.0",
      "date": "2026-10-14T09:04:00.000Z",
      "distro": "resolute",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/97dd9ede720ef0104035db5e1bd15700861277eb9745967473af9f034051e867",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    },
    {
      "r": "4.6.1",
      "os": "linux",
      "version": "0.1.0",
      "date": "2026-10-14T09:03:20.000Z",
      "distro": "resolute",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/93cbe35d38b3408951cbd099fe51603b67aaa0cc1d06ba8e450fe3749aa4d0cc",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "0.1.0",
      "date": "2026-10-14T09:49:10.000Z",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/1f6f31d11308a03953f8fc7b5b4a6db2512bac12c941f893a55a0fe6e3b928a5",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    },
    {
      "r": "4.6.1",
      "os": "mac",
      "version": "0.1.0",
      "date": "2026-10-14T09:45:10.000Z",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/f64f12b6a192ab5d022fe4e2678aeac992309d7402bf97fa7f76a2cc35eceb07",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "0.1.0",
      "date": "2026-10-14T09:03:20.000Z",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/abbdd793b7205052c0bafb76488c3ca61ef97752cfcfdacf4521552920eb66df",
      "status": "success",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "0.1.0",
      "date": "2026-10-14T09:02:51.000Z",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/20fda38ae9b9eaca69e17005a5ce67a4c64debe86b6a3d4268ecfea34db0b2ea",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "0.1.0",
      "date": "2026-10-14T09:02:36.000Z",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/c381bc7db96f94f59db9d0bf44f0933896cc196872d1e5d0abbc26b3bd305517",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    },
    {
      "r": "4.6.1",
      "os": "win",
      "version": "0.1.0",
      "date": "2026-10-14T09:02:54.000Z",
      "commit": "a61383993f2ee07cc2a06bce92d097a985223839",
      "fileid": "https://r2.ropensci.org/2796521348afd1ca152d3d077562c5a8c1de861478e5255d290f9db04403bd2c",
      "status": "success",
      "check": "OK",
      "buildurl": "https://github.com/r-universe/edelmand21/actions/runs/38539015715"
    }
  ]
}